Ejaculation could be defined as a process which involves the secretion of seminal fluid from the prostate and seminal vesicle contraction of smooth muscles of the seminal tract. There are at least three serotonin receptor which has been identified to have a important role of ejaculation which include 5-HT1a, 5-HT1b, and 5HT2c. The activation of 5HT 1b and 5HT 2c receptors leads to delaying of ejaculation process. The mechanism of action of Dapoxetine is mainly due to inhibition of neuronal uptake and involve a number of regulatory neurotransmitters, the most widely studied of which is 5-hydroxytryptamine (5-HT) or serotonin.
The starting recommended dose in case of starters is 30 mg. It could be taken at least one to three hours before the sexual act. The maximum dose is once in twenty four hours. Incas the 30 mg is insufficient the dose can be increased to 60 mg.
The most common side effects which are observed after taking the medication includes nausea, dizziness, dry mouth, headache, diarrhea and insomnia
There are many precautions which could be taken with the medications as to prevent any adverse outcome.
If you are planning to take Dapoxetine, along with alcoholic beverages or alcohol you should discuss with the doctor before starting it.
Avoid the use of recreational drugs such as ecstasy when you are using Dapoxrtine pills.
Narcotics and psychotropic drug should be totally avoided or discussed with doctor for safety purpose.
In case of bipolar disorder discuss with the doctor before taking the drug.
In case of moderate to severe renal disease, talk to your doctor before you start the pill.
In Case of epilepsy proper suggestion from your doctor is must before you plan to take the medication.
In case of orthostatic hypotension discuss with the doctor.
If you are pregnant or a lactating mother discuss with the doctor because you are in a precautionary stage.
The medication has shown effect of dizziness. So driving car pt operating any heavy machinery should be avoided.
In case of serious hypersensitivity to any of the ingredient of Poxet, you should not take the medication.
In case of certain cardiac conditions like ischemic heart disease and conduction abnormalities the medication should not be given.
In case of moderate to severe hepatic impairment stop using the medication.
Concomitant administration of Monoamine Oxidase Inhibitor (MAOI) should be avoided. You need to wait for at least 14 days after stopping the medication.
CYP3 A4 Inhibitors like Itraconazole, Nelfinavir should be avoided along with Dapoxetine as they inhibit the metabolism of the drug, thereby leading to increased plasma concentration of the drug.
No case of overdose is reported with Dapoxetine.
As the drug is taken when desired, there are no cases of missed doses. But in case it is prescribed by your physician take it as soon as you remember.
The medication is taken stored below thirty degree Celsius. It should be kept in a cool and dry place. It should be kept away from children and pets.
|Generic||Poxet | Dapoxetine Tablets|
|Strength||Poxet | Dapoxetine Tablets|